发明名称 IMPROVED CANCER TREATMENT WITH TEMOZOLOMIDE
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a method for the treatment of a patient suffered from cancer. <P>SOLUTION: The method for the treatment of a patient suffered from cancer comprises the administration of temozolomide to the patient for at least two cycles of a cyclical dosing schedule, wherein each cycle has a dosing period of 5-25 days, in which temozolomide is administered daily at a dose of 40-150 mg/m<SP>2</SP>/day, followed by a rest period of 5-14 days in which temozolomide is not administered. Also provided is a medical kit for administering temozolomide, having printed instructions for administering temozolomide according to the above cyclical dosing schedule and a supply of temozolomide in dosage units for at least one cycle, wherein each dosage unit contains 5-250 mg of temozolomide and a pharmaceutically acceptable carrier. <P>COPYRIGHT: (C)2007,JPO&INPIT</p>
申请公布号 JP2007169297(A) 申请公布日期 2007.07.05
申请号 JP20070073722 申请日期 2007.03.20
申请人 SCHERING PLOUGH CORP 发明人 RAGAB MOHAMED H
分类号 A61K31/4188;C07D487/04;A61K31/41;A61P35/00 主分类号 A61K31/4188
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