EUKARYOTIC CELL DIVISION GENES AND THEIR USE IN DIAGNOSIS AND TREATMENT OF PROLIFERATIVE DISEASES
摘要
The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in cell division and proliferation processes that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologues of said genes including all biologically-active derivatives thereof. The invention further relates to the use of said gene products (including said orthologues) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative diseases.
申请公布号
WO0238805(A8)
申请公布日期
2007.07.05
申请号
WO2001EP13034
申请日期
2001.11.09
申请人
CENIX BIOSCIENCE GMBH;ECHEVERRI, CHRISTOPHE;GOENCZY, PIERRE;HYMAN, ANTHONY;JONES, STEVEN;OEGEMA, KAREN;KIRKHAM, MATTHEW
发明人
ECHEVERRI, CHRISTOPHE;GOENCZY, PIERRE;HYMAN, ANTHONY;JONES, STEVEN;OEGEMA, KAREN;KIRKHAM, MATTHEW