Process for detecting PrP using a macrocyclic adjuvant ligand

摘要

A process for detecting the forms of the prion pathogens responsible for subacute, transmissible, spongiform encephalopathies, including a macrocyclic adjuvant ligand (AML), free or bound to a support, that is added to a biological sample capable of containing PrP^sc, the resulting suspension then being reacted with an anti-PrP^sc antibody, and the presence of PrP is then detected.