MANNOSE-BINDING LECTIN KNOCK-OUT MICE AND METHODS OF USE THEREOF
摘要
A transgenic non-human animal with alterations in the MBL gene is prepared by introduction of a gene encoding an altered MBL protein into a host non-human animal. Methods for using transgenic mice so generated to screen for agents that effect MBL's cellular modulating activity are also provided.
申请公布号
WO2006073432(A3)
申请公布日期
2007.07.05
申请号
WO2005US13549
申请日期
2005.04.20
申请人
THE GENERAL HOSPITAL CORPORATION;TAKAHASHI, KAZUE;EZEKOWITZ, R., ALAN;SHI, LEI