HSP90 INHIBITORS, METHODS OF MAKING AND USES THEREFOR
摘要
The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer and other proliferative tissue disorders.
申请公布号
WO2006098761(A3)
申请公布日期
2007.07.05
申请号
WO2005US31524
申请日期
2005.08.31
申请人
THE REGENTS OF THE UNIVERSITY OF COLORADO;ROSS, DAVID;REIGAN, PHILIP;GUO, WENCHANG;SIEGEL, DAVID;GUSTAFSON, DANIEL, L.
发明人
ROSS, DAVID;REIGAN, PHILIP;GUO, WENCHANG;SIEGEL, DAVID;GUSTAFSON, DANIEL, L.
