<p>The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.</p>
申请公布号
WO2007075186(A2)
申请公布日期
2007.07.05
申请号
WO2006US14486
申请日期
2006.04.17
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;NIZET, VICTOR;LIU, GEORGE, Y.