发明名称 |
METHOD OF INHIBITING MELANOSOME MIGRATION USING PROHIBITION SIRNA |
摘要 |
A method for inhibiting melanosome migration by using prohibitin siRNA(small interference RNA) is provided to inhibit expression of prohibitin in a melanin synthesis cell and uniformed distribution of melanosome in the melanin synthesis cell, so that the skin is whitened. The melanosome migration to the end of melanin synthesis cell is inhibited by administering prohibitin siRNA into the melanin synthesis cell, melan-a, thereby inhibiting binding of prohibitin to melanophilin as a melanosome vehicle and uniformed distribution of melanosome in the melanin synthesis cell. |
申请公布号 |
KR20070070300(A) |
申请公布日期 |
2007.07.04 |
申请号 |
KR20050069505 |
申请日期 |
2005.07.29 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
CHANG, HUI KYOUNG;KIM, DAE GUN;LEE, TAE RYONG;CHO, SI YOUNG;AHN, SOO MI;HWANG, JAE SUNG |
分类号 |
C07K14/00;A61K8/64 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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