NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION

摘要

The present invention relates to a compound represented by the general formula (I): wherein Ra and Rb are each independently hydrogen atom or lower alkyl, or alternatively Ra and Rb are combined together to form-CH2-; Rc is halogen atom; Rd is halogen atom or methyl substituted with one to three halogen atoms; X is CH, N, etc. ; and W is selected from: wherein W1 is hydrogen atom, halogen atom, etc., or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition or antitumor agent containing the same; and combinations of the antitumor agent with other antitumor agent(s).