发明名称 |
NOVEL GLUCITOL DERIVATIVE AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES |
摘要 |
The invention provides a glucitol derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity; and a medicinal composition for use in the prevention or treatment of diseases attributable to hyperglycemia, such as diabetes, complications of diabetes, and obesity. The derivative is a compound represented by the formula (I):
wherein m is an integer selected among 1-3; R 1 to R 4 each independently is optionally substituted alkyl, etc.; Ar1 is optionally substituted naphthyl; and A is optionally substituted heteroaryl, a prodrug of the compound, or a pharmaceutically acceptable salt of either. Also provided are a medicine, a medicinal composition, and the like each containing the compound.
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申请公布号 |
EP1803721(A1) |
申请公布日期 |
2007.07.04 |
申请号 |
EP20050767034 |
申请日期 |
2005.07.27 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
MATSUOKA, HIROHARU;SATO, TSUTOMU;NISHIMOTO, MASAHIRO;KATO, YASUHARU;SAKAITANI, MASAHIRO;LEE, SANG-HAK |
分类号 |
C07D409/10;A61K31/381;A61P3/10;C07H7/04;E04F13/08;F16B13/04;F16B13/10 |
主分类号 |
C07D409/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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