| 摘要 |
A two-compartment type prefilled syringe (K1) including a first rubber stopper (6) fitted into a front sleeve (7), a second rubber stopper (9) fitted into a rear end portion of a cartridge (1), a third rubber stopper (12) for hermetically dividing interior of the cartridge (1) into front and rear compartments (14, 16) and a bypass (18) formed by radially outwardly bulging a portion of a peripheral wall of the cartridge (1), wherein in an axial direction of the cartridge (1), a length (20) of the third rubber stopper (12) is slightly smaller than an inner length (19) of the bypass (18), wherein when the third rubber stopper (12) has been displaced into the bypass (18), sealing property of the rear compartment (16) against the front compartment (14) is cancelled such that dissolving agent (15), suspension or the like in the rear compartment (16) is carried, via the bypass (18), into the front compartment (14) containing dry medicament (13) or the like, wherein a ratio (R) of a maximum width (b) of one end of the bypass (18) adjacent to the front sleeve (7) to a maximum width (a) of the other end of the bypass (18) adjacent to the rear end portion of the cartridge (1) is set to range from 1.2 to 5.0. <IMAGE> |
