发明名称 Pyrazole compounds for treatment of neurodegenerative disorders
摘要 The invention provides compounds of Formula I: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, and A are as defined. Compounds of formula I have activity inhibiting production of Abeta-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula I.
申请公布号 US7238721(B2) 申请公布日期 2007.07.03
申请号 US20030680488 申请日期 2003.10.07
申请人 PFIZER INC 发明人 CHEN YUHPYNG L.;LIRAS SPIROS;ROSATI ROBERT L.;ALLEN MARTIN P.
分类号 A61K31/4152;A61P25/00;C07D231/40;C07D401/06;C07D401/12;C07D403/04;C07D403/06;C07D405/04;C07D409/04;C07D409/12;C07D413/14;C07D471/04;C07D487/04 主分类号 A61K31/4152
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