METHOD FOR PREPARING OF A POROUS OSTEOCHONDRAL COMPOSITE SCAFFOLD

摘要

Provided is a porous osteochondral composite scaffold with layer structure which has features of bioactivation and mechanical strength suitable to regenerate cartilage and bone simultaneously and method for manufacturing the same. The porous osteochondral composite scaffold comprises: a porous bone regeneration layer which includes biocompatable high molecule and bioactivation ceramic; a porous cartilage regeneration layer which includes biocompatable elastic high molocule. The method for manufacturing a porous osteochondral composite scaffold comprises the steps of: mixing biocompatable high molecule, bioactivation ceramic and lacuna-forming material; press-forming the mixed material from the first step in a mold; bonding the obtained material from the second step by heating to form a porous bone regeneration layer; forming composite material by press-forming gelled mixed material for forming cartilage which dissolves in solution with biocompatable high molecule and lacuna-forming material on one surface of the regenerated layer from the third step; removing solution and lacuna-forming material in the composite material from the fourth step.