发明名称 |
METHODS FOR FINE POWDER FORMATION |
摘要 |
Improved methods for forming fine particles of a material have been develope d, wherein the method steps include dissolving the material in a solvent to for m a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilu te solution include freezing, gelation, and chelation. In a preferred embodimen t, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.
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申请公布号 |
CA2367131(C) |
申请公布日期 |
2007.07.03 |
申请号 |
CA20002367131 |
申请日期 |
2000.04.05 |
申请人 |
PHARMACEUTICAL DISCOVERY CORPORATION |
发明人 |
STEINER, SOLOMON S.;FELDSTEIN, ROBERT |
分类号 |
A61J3/02;A61K9/19;A61K9/00;A61K9/16;A61K31/7115;A61K38/00;A61K47/36;A61K47/38;A61K47/42;F26B5/06 |
主分类号 |
A61J3/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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