发明名称 |
Cationic liposome delivery of taxanes to angiogenic blood vessels |
摘要 |
Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
|
申请公布号 |
US7238369(B2) |
申请公布日期 |
2007.07.03 |
申请号 |
US20050199616 |
申请日期 |
2005.08.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MCDONALD DONALD M.;MCLEAN JOHN W.;THURSTON O. GAVIN |
分类号 |
A61K9/127;A61K31/337;A61K47/48;A61K49/00;C12N15/88 |
主分类号 |
A61K9/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|