TOPICAL COMPOSITION AND METHOD FOR ENHANCING LIPID BARRIER SYNTHESIS

摘要

The present invention relates to topical com-positions useful in enhancing lipid synthesis in skin comprising an effective amount of cafestol or kahweol, or derivative thereof, in combination with a pharmaceutically or cosmetically acceptable carrier. Such compositions are useful in treatment or prevention of dry skin and conditions in which the skin's lipid barrier is defective or damaged. Figure 5 shows increased ceramide synthesis with cafestol.