| 摘要 |
NOVEL QUATERNARY AMMONIUM COMPOUNDS OF THE FORMULA AND ANY STEREO ISOMERS THEREOF, WHEREIN R1, R2 AND R3 INDEPENDENTLY REPRESENT C1-C6 ALKYL,OPTIONALLY SUBSTITUTED WITH PHENYL OR HYDROXYL, OR BOTH, AND WHEREIN ANY TWO OF R1, R2 AND R3 MAY FORM A RING TOGETHER WITH THE QUATERNARY AMMONIUM NITROGEN; R4 REPRESENTS —H, —CH3, OR —CO—R4-1, WHEREIN R4-1 REPRESENTS — (C1-C4 ALKYL), — (C1-C4 ALKOXY), OR —NR4-2 R4-3, WHEREIN R4-2 AND R4-3 INDEPENDENTLY REPRESENT -H OR — (C1-C4 ALKYL); R5, R6 AND R7 INDEPENDENTLY REPRESENT -H, -OCH3, —OH, —CONH2, —SO2 NH2, —F, —CI, —BR, —I, —CF3, OR— (C1-C4 ALKYL), OPTIONALLY SUBSTITUTED WITH ONE OR TWO —OH, —(C1-C4 ALKOXY), —COOH, OR —CO—O—(C1-C3 ALKYL); AND X-REPRESENTS AN ANION OF A PHARMACEUTICALLY ACCEPTABLE ACID, THE COMPOUNDS FOR USE AS MEDICAMENTS, USE OF THE COMPOUNDS FOR THE MANUFACTURE OF SPECIFIC MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS.THE PRESENT INVENTION ALSO CONCERNS THE USE OF THE COMPOUND FOR THE MANUFACTURE OF A MEDICAMENT FOR A SPECIFIED MEDICAL USE.
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