发明名称 THE USE OF CYTOKINE ABLE TO BIND IL-18BP AND OF INHIBITING THE ACTIVITY OF A SECOND CYTOKINE
摘要 The present invention relates to the use of a cytokine-1, preferably from the IL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein, functional derivative or fragment thereof, capable of binding to IL-18 BP or a mutein, fused protein, functional derivative or fragment thereof and capable of inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for the treatment or prevention of a disease which is caused or aggravated by inducing said receptor of cytokine-2.
申请公布号 EA008667(B1) 申请公布日期 2007.06.29
申请号 EA20050000617 申请日期 2003.10.03
申请人 ARES TRADING S.A. 发明人 DINARELLO CHARLES, A.;KIM SOO-HYUN;BUFLER PHILIP
分类号 A61K38/20;A61K38/17;A61K38/19;A61P29/00 主分类号 A61K38/20
代理机构 代理人
主权项
地址