Recoverable intra-uterine device for use in field of in vivo or in utero fertilization, has housing with wall including series of perforations with size that is sufficient to bring intra-uterine medium in cellular contact with housing

摘要

#CMT# #/CMT# The device has a housing (11) containing elements selected from a group containing an embryo, male and/or female gametes, a fertilized oocyte, an unfertilized egg and a combination of the elements. The housing (11) has a wall made of a polymer ceramic or glass type transparent biocompatible material or elastomer material. The wall has a series of perforations (12) with a size that is sufficient to bring an intra-uterine medium in cellular contact with the housing. #CMT#USE : #/CMT# Recoverable intra-uterine device for implanting and for transitorily maintaining elements selected from a group containing an embryo, male and/or female gametes, a fertilized oocyte, an unfertilized egg and the combination of the elements (all claimed), in an uterus, for use in field of in vivo or in utero fertilization in reproduction methods assisted with preimplantation development and/or fertilization techniques. #CMT#ADVANTAGE : #/CMT# The series of perforations in the wall of the housing has size sufficient to bring the intra-uterine medium in cellular contact with the housing, thus increasing exchanges with uterine matrix in a reliable and reproducible manner and facilitating the development of embryos, while ensuring reimplantation and nidation of the embryo in the uterus in an easy manner. The device presents better rigidity to implant the embryo or gametes and to introduce or remove the device in the uterus. The device can be loaded or unloaded without altering quality of embryos or other elements loaded in the housing. The wall is made of transparent biocompatible material, thus facilitating visualization of gametes and embryo in the device during loading and unloading of the device, and hence facilitating the manipulation of the device in the safe manner. #CMT#DESCRIPTION OF DRAWINGS : #/CMT# The drawing shows a schematic perspective view of a housing of a recoverable intra-uterine device. 11 : Housing 11a : Distal end 11b : Proximal end 12 : Perforations #CMT#METALLURGY : #/CMT# The wall is made of metal alloy e.g. stainless steel, titanium or titanium alloy.