The invention relates to a method of producing a HPV polypeptides and/or an influenza virus H5 polypeptide in a plant comprising the steps of cloning a HPV gene; and/or an influenza virus H5 gene or nucleic acid encoding their functional equivalents into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the HPV polypeptides and/or an influenza virus H5 polypeptide, and/or to create a transgenic plant; and recovering the HPV polypeptides and/or an influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method.
申请公布号
WO2006119516(A3)
申请公布日期
2007.06.28
申请号
WO2006ZA00063
申请日期
2006.05.02
申请人
UNIVERSITY OF CAPE TOWN;WILLIAMSON, ANNA-LISE;RYBICKI, EDWARD, PETER;MACLEAN, JAMES, MALCOLM;BECKER-HITZEROTH, INGA, ISABEL