发明名称 |
Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiogenesis |
摘要 |
The invention describes an isolated polynucleotide having a nucleotide sequence which encodes a polypeptide capable of inhibiting angiogenesis or neovascularization and which nucleotide sequence is at least 95 percent identical to a sequence selected from the group consisting of a sequence that encodes the polypeptide of SEQ ID NO:7, a sequence that encodes the polypeptide of SEQ ID NO: 12 and a sequence that encodes a fragment of the polypeptide of SEQ ID NO: 12. A vector comprising said isolated polynucleotide, recombinant host cells including said isolated polynucleotide or said vector, and uses of said polynucleotide, said vector, or the polypeptide encoded by said isolated polynucleotide are also provided. |
申请公布号 |
AU2002306558(B2) |
申请公布日期 |
2007.06.28 |
申请号 |
AU20020306558 |
申请日期 |
2002.02.22 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
PAUL SCHIMMEL;KEISUKE WAKASUGI;MARTIN FRIEDLANDER |
分类号 |
G01N33/50;A61K9/08;A61K38/00;A61K38/53;A61K48/00;A61P9/00;A61P27/02;C07H21/00;C07K2/00;C12N1/14;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N15/09;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|