| 摘要 |
PROBLEM TO BE SOLVED: To provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc. SOLUTION: A pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. COPYRIGHT: (C)2007,JPO&INPIT
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