<p>Subject of the invention is a compound, consisting of a targeting moiety which specifically binds to a disease related cell surface marker, a nucleic acid which specifically induces cell death and a linker, wherein the linker covalently links the targeting moiety to the nucleic acid. Subject of the invention are also medicaments comprising the compound and their use as a medicament for the treatment of diseases, including proliferative diseases.</p>
申请公布号
WO2007071777(A2)
申请公布日期
2007.06.28
申请号
WO2006EP70116
申请日期
2006.12.21
申请人
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;BARTH, STEFAN;WUELLNER, ULRICH;NEEF, INGA