A TAXANE DERIVATIVE CONTAINING PHARMACEUTICAL COMPOSITION WITH IMPROVED THERAPEUTIC EFFICACY

摘要

The invention relates to a liquid pharmaceutical composition comprising (a) an effective amount of at least one taxane derivative, (b) an effective amount of at least one poly-unsaturated fatty acid or a derivative thereof and/or at least one hydrophobic vitamin or a derivative thereof, and (c) at least one pharmaceutically acceptable carrier and a process for the preparation of the same. The composition can be used for the therapy of cancers which are sensitive to taxane derivatives. The invention also relates to a a pharmaceutical combination comprising components (a) and (b) and to a kit comprising the individual components of the above mentioned composition placed in separate containers.