发明名称 |
Preparation for repairing cartilage tissue, especially articular cartilage defects |
摘要 |
The invention relates to preparations which are suitable for repairing enchondral or osteochondral defects ( 4 ) by means of implantation, said preparations comprising a cartilage element (A) and optionally a bone element (B) which is connected to the cartilage element (A). The cartilage element (A) can already contain cells during the implantation or is populated after the implantation with cells migrating from surrounding tissue. The aim of the invention is to better equip the cartilage element (A) of one such preparation for integration into the surrounding tissue and/or for an easy-to-achieve, primary stability. To this end, said cartilage element is not homogeneously embodied but has different characteristics in a peripheral and/or basal region ( 2, 3 ) to those in a central region ( 3 ). Said differing characteristics (A) relate to the structure and/or composition of the matrix used and/or to the cells established in the matrix, and are in no way used to prevent the migration of cells into the preparation from the surrounding tissue.
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申请公布号 |
US2007148242(A1) |
申请公布日期 |
2007.06.28 |
申请号 |
US20040547437 |
申请日期 |
2004.02.23 |
申请人 |
ZIMMER ORTHOBIOLOGICS, INC |
发明人 |
VILEI SIMONA B.;BITTMANN PETER;WAGNER PHILIPP;FRENZ MARTIN |
分类号 |
A61K9/14;A61F2/00;A61F2/02;A61F2/28;A61F2/30;A61F2/38;A61L27/38;A61L27/56 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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