AMIDE DERIVATIVES AS ROCK INHIBITORS

摘要

This invention relates to novel amide derivatives and salts thereof. More particularly, it relates to novel amide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease. In the formula wherein A is lower alkyl, optionally substituted aryl, optionally substituted cycloalkyl or optionally substituted heterocyclic group; L₁ is -H or -NH₂; L₂ is CR₁₄ or N; L₃ is CH or N; L₄ is CR₂ or N.