IMPROVER FOR DETERIORATION IN PRODUCTION OF TGF-beta RECEPTOR

摘要

PROBLEM TO BE SOLVED: To provide an improver for deterioration in production of a TGF (transforming growth factor)-β receptor with ultraviolet light and an improver for deterioration in production of collagen with the ultraviolet light improving the deterioration in production of the TGF-β receptor with the ultraviolet light, preventing the deterioration in production of the collagen and thereby carrying out prophylaxis and improvement of the formation of wrinkles or deterioration in elasticity and to provide an anti-aging external preparation for skin.

SOLUTION: The improver for the deterioration in production of the TGF-β receptor with the ultraviolet light and improver for deterioration in production of the collagen with the ultraviolet light are characterized as comprising a cultured product of Zymomonas mobilis. The anti-aging external preparation for skin is characterized as comprising the cultured product of the Zymomonas mobilis and a hybrid cell extract from Luffa cylindrica M. Roemen and Gynostemma pentaphyllum. The reduction in the amount of the collagen produced is prevented and the prophylaxis and improvement of the formation of the wrinkles or deterioration in the elasticity found in photo-aged skin are carried out by suppressing the deterioration in production of the TGF-β receptor with the ultraviolet light. Furthermore, the formation of the wrinkles and deterioration in the elasticity are prevented and improved by using the cultured product of the Zymomonas mobilis and a hybrid cell extract from the Luffa cylindrica M. Roemen and Gynostemma pentaphyllum in combination.

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