发明名称 |
(INDAZOL-5-YL)-PYRAZINES AND (1,3-DIHYDRO-INDOL-2-ONE)-PYRAZINES FOR TREATING RHO KINASE-MEDIATED DISEASES AND CONDITIONS |
摘要 |
Methods for using (indazol-5-yl)-pyrazines and (1,3-dihydro-indol-2-one)-pyrazines are disclosed herein to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of (indazol-5-yl)-pyrazines and (1,3-dihydro-indol-2-one)-pyrazines, are disclosed herein.
|
申请公布号 |
US2007149548(A1) |
申请公布日期 |
2007.06.28 |
申请号 |
US20060612894 |
申请日期 |
2006.12.19 |
申请人 |
ALCON MANUFACTURING, LTD. |
发明人 |
HELLBERG MARK R.;SHARIF NAJAM A.;MAY JESSE A.;RUSINKO ANDREW;CHEN HWANG-HSING |
分类号 |
A61K31/497;A61K31/4965;A61K31/557 |
主分类号 |
A61K31/497 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|