发明名称 |
Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole |
摘要 |
The present invention relates to methods of preparing a highly pure crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone, which is a chemical intermediate useful in the preparation of Aripiprazole thereof in high quality and yield, and provides data that characterizes the crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone.
|
申请公布号 |
US2007149782(A1) |
申请公布日期 |
2007.06.28 |
申请号 |
US20050315230 |
申请日期 |
2005.12.23 |
申请人 |
BRAND MICHAEL;SHOOKRUN MOTY;GRIBUN IRINA;ADIN ITAI;IUSTAIN CARMEN;BRAVERMAN OLEG;UDIS NATALIA;ARAD ODED;KASPI JOSEPH |
发明人 |
BRAND MICHAEL;SHOOKRUN MOTY;GRIBUN IRINA;ADIN ITAI;IUSTAIN CARMEN;BRAVERMAN OLEG;UDIS NATALIA;ARAD ODED;KASPI JOSEPH |
分类号 |
A61K31/496;C07D403/02 |
主分类号 |
A61K31/496 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|