发明名称 Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole
摘要 The present invention relates to methods of preparing a highly pure crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone, which is a chemical intermediate useful in the preparation of Aripiprazole thereof in high quality and yield, and provides data that characterizes the crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone.
申请公布号 US2007149782(A1) 申请公布日期 2007.06.28
申请号 US20050315230 申请日期 2005.12.23
申请人 BRAND MICHAEL;SHOOKRUN MOTY;GRIBUN IRINA;ADIN ITAI;IUSTAIN CARMEN;BRAVERMAN OLEG;UDIS NATALIA;ARAD ODED;KASPI JOSEPH 发明人 BRAND MICHAEL;SHOOKRUN MOTY;GRIBUN IRINA;ADIN ITAI;IUSTAIN CARMEN;BRAVERMAN OLEG;UDIS NATALIA;ARAD ODED;KASPI JOSEPH
分类号 A61K31/496;C07D403/02 主分类号 A61K31/496
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