发明名称 |
Solid oral dosage form containing an enhancer |
摘要 |
The invention relates to a pharmaceutical composition and oral dosage forms comprising an HDAC inhibitor in combination with an enhancer to promote absorption of the HDAC inhibitor at the GIT cell lining. The enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms. Preferably, the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
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申请公布号 |
US2007148228(A1) |
申请公布日期 |
2007.06.28 |
申请号 |
US20060450641 |
申请日期 |
2006.06.09 |
申请人 |
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发明人 |
CUMMING KENNETH I.;RAMTOOLA ZEBUNNISSA;LEONARD THOMAS W. |
分类号 |
A61K38/12;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K31/19;A61K31/403;A61K47/12 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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