摘要 |
A compound represented by the formula: (wherein, R<SUP>1 </SUP>and R<SUP>2 </SUP>are the same or different and each represents a hydrogen atom, hydrocarbon group or heterocyclic group, or R<SUP>1 </SUP>and R<SUP>2 </SUP>may form, together with the adjacent carbon atom, a 3-8 membered iso- or heterocyclic group, R<SUP>3 </SUP>represents a cyclic group, a hydroxy group, a mercapto group that may have oxo, or an amino group, R<SUP>4 </SUP>represents a hydrogen atom, a hydrocarbon group, a hydroxy group, a mercapto group which may have oxo, or an amino group, or R<SUP>2 </SUP>and R<SUP>4 </SUP>may link together to form a double bond, X represents a bond or a linear hydrocarbon group, W represents an oxygen atom or a sulfur atom, ring B represents a 5-8 membered nitrogen-containing heterocyclic group, ring C represents a benzene ring, and <img id="custom-character-00001" he="1.78mm" wi="6.35mm" file="US20070149558A1-20070628-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/> represents a single bond or a double bond), or a salt or a prodrug thereof that has excellent neurodegenerative inhibitory activity and brain penetrability, and is useful as an agent for preventing/treating neurodegenerative diseases.
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