发明名称 |
TREATMENT OF BONE DISORDERS |
摘要 |
<p>Methods of treatment of various bone indications, such as osteoporosis, in a mammal are provided wherein an effective amount of an antagonist that .binds to a B-cell surface marker, such as a CD20 antibody, is administered, optionally also with another medicament such as an agent that treats such disorders in an effective amount. Articles of manufacture are also provided. Further, a method of inhibiting osteolysis in a mammal is provided comprising introducing into said mammal an isolated odontoprogenitor or osteoprogenitor cell comprising a nucleic acid encoding an antibody that binds to a B-cell surface marker.</p> |
申请公布号 |
WO2006093923(B1) |
申请公布日期 |
2007.06.28 |
申请号 |
WO2006US06998 |
申请日期 |
2006.02.28 |
申请人 |
GENENTECH, INC.;SEWELL, LEA, K.;QUAN, JOANNE |
发明人 |
SEWELL, LEA, K.;QUAN, JOANNE |
分类号 |
C07K16/28;A61K39/395 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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