发明名称 NOVEL PROLINE-DERIVATIVE BASED COSMETOLOGICAL AND/OR DERMATOLOGICAL COMPOSITIONS AND USES THEREOF
摘要 <p>The present invention relates to the necessities of life, and more particularly to the field of cosmetology and dermatology. It relates more particularly to novel cosmetological and/or dermatological compositions which bring about a very significant increase in the deposition of collagen type (III) in the extracellular matrix, characterized in that they contain, as active ingredient, a combination of a 4-hydroxyproline fatty acid amido ester, of formula (I): in which R&lt;SUB&gt;1&lt;/SUB&gt; and R'&lt;SUB&gt;1&lt;/SUB&gt; are identical or different aliphatic chains containing from 10 to 24 carbon atoms that are in a straight line or branched, and of an extract of the epicarp of the Opuntia ficus-indica (Barbary fig) fruit in an inert, nontoxic excipient or carrier suitable for topical use. Use in the form of a fatty cream or gel for the increased production of collagen, without amplifying that of procollagen (III) or of enzymes of the metalloproteinase family.</p>
申请公布号 WO2007072178(A1) 申请公布日期 2007.06.28
申请号 WO2006IB03695 申请日期 2006.12.19
申请人 TEXINFINE;INNOVAT;GRIMAUD, JEAN, ALEXIS;GUTIERREZ, GILLES;SERRAR, MOSTAFA 发明人 GRIMAUD, JEAN, ALEXIS;GUTIERREZ, GILLES;SERRAR, MOSTAFA
分类号 A61K36/33;A61K8/49;A61K8/97;A61K31/4015;A61P17/00;A61Q19/08 主分类号 A61K36/33
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