发明名称 CXCR3 antagonists
摘要 Compounds, compositions and methods are provided that are useful in the treatment of conditions and diseases mediated by a chemokine receptor. In particular, the compounds of the invention modulate the CXCR3 chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
申请公布号 US2007149557(A1) 申请公布日期 2007.06.28
申请号 US20060603699 申请日期 2006.11.21
申请人 AMGEN INC. 发明人 COLLINS TASSIE L.;MEDINA JULIO C.;XU FENG;ZHU LIUSHENG
分类号 A61K31/4747;C07D471/14 主分类号 A61K31/4747
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