发明名称 Pharmaceutical composition comprising (E) -7- [4- (4-fluorophenyl) -6-isopropyl-2- [methyl (methylsulfonyl) amino] pyrimidin-5 -yl- (3R, 5S) -3, 5-dihydr0xyhept-6-en0ic acid
摘要 A chemically stable formulation of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof for oral use, such as tablets, capsules, powders, granules has been developed using the substances which stabilize against formation of degradation products: lactone and oxidation product.
申请公布号 AU2006329006(A1) 申请公布日期 2007.06.28
申请号 AU20060329006 申请日期 2006.12.18
申请人 LEK PHARMACEUTICALS D.D. 发明人 KLEMEN NAVERSNIK;MIHA TOMAZ JAKLIC
分类号 A61K31/505;A61P3/06;A61P9/10 主分类号 A61K31/505
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