摘要 |
The present invention relates to the use of a compound of formula (I) wherein R1 and R2 together form an oxo group, or a pharmaceutically acceptable salt thereof, for the treatment of agitation, in particular behavioral agitation, especially in dementia patients diagnosed with Alzheimer's disease; pharmaceutical compositions comprising a compound of formula I; in combination with at least one compound selected from the group consisting of nootropic plant extracts, calcium antagonists, cholinesterase inhibitors, dihydroergotoxin, nicergoline, piracetame, purine derivates, pyritinol, vincamine and vinpocetin; and a kit including instructions for us of the combination. |