发明名称 Brain-associated inhibitor of tissue-type plasminogen activator
摘要 The present invention relates to a novel BAIT protein which is a member of serpin superfamily which is expressed primarily in brain tissue. In particular, isolated nucleic acid molecules are provided encoding the human and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of BAIT activity. Also provided are diagnostic methods for detecting nervous system-related disorders and therapeutic methods for treating nervous system-related disorders. Additionally, the present invention is related to methods of treating patients with BAIT polynucleotides or polypeptides, wherein said patients have had seizures or epilepsy.
申请公布号 US7235529(B2) 申请公布日期 2007.06.26
申请号 US20040752041 申请日期 2004.01.07
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 COLEMAN TIMOTHY A.;LAWRENCE DANIEL A.;YEPES MANUEL
分类号 A61K38/57;A61K38/00;A61K39/00;C07K14/47;C07K14/81;C12P21/06 主分类号 A61K38/57
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