摘要 |
This invention provides estrogen receptor modulators of formula I, having the structure wherein, R<SUB>1 </SUB>is hydrogen, alkyl of 1-6 carbon atoms, benzyl, alkylcarbonyl of 2-7 carbon atoms, or benzoyl; X is R<SUB>2 </SUB>is hydrogen, alkyl of 1-6 carbon atoms, benzyl, alkylcarbonyl of 2-7 carbon atoms, or benzoyl; R<SUB>3 </SUB>is hydrogen, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable salt of a sulfate ester of the hydroxyl group at the 3- or 17-position when R1 or R2 is hydrogen, or a glucuronide of the hydroxyl group at the 3- or 17-position when R1 or R2 is hydrogen.
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