发明名称 Azaspiroalkanderivat som hämmare av metalloproteaser
摘要 The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
申请公布号 SE0701538(A) 申请公布日期 2007.06.26
申请号 SE20070001538 申请日期 2007.06.26
申请人 INCYTE CORP 发明人 WENQING YAO;JINCONG ZHOU;MEIZHONG XU;FENGLEI ZHANG;BRIAN METCALF
分类号 C07D221/20;A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/438;A61K31/4418;A61K31/444;A61K31/4747;A61K31/496;A61P9/00;A61P17/00;A61P19/02;A61P29/00;A61P35/00;C07D;C07D207/08;C07D211/60;C07D295/185;C07D401/06;C07D401/14;C07D471/04;C07D471/10;C07D491/10;C07D497/10 主分类号 C07D221/20
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