| 发明名称 |
THERAPY FOR .ALPHA.-GALACTOSIDASE A DEFICIENCY |
| 摘要 |
<p>A therapeutic method whereby an individual suspected of having an .alpha.- galactosidase A deficiency, such as Fabry disease, is treated either with (I) human cells that have been genetically modified to overexpre ss and secrete human .alpha.-gal A, or (2) purified human .alpha.-gal A obtained from cultured, genetically modified human cells.</p> |
| 申请公布号 |
CA2265464(C) |
申请公布日期 |
2007.06.26 |
| 申请号 |
CA19972265464 |
申请日期 |
1997.09.12 |
| 申请人 |
TRANSKARYOTIC THERAPIES, INC. |
发明人 |
KINOSHITA, CAROL M.;GILLESPIE, FRANCES P.;WILLIAMS, MELANIE D.;BOROWSKI, MARIANNE;TRECO, DOUGLAS A.;SELDEN, RICHARD F. |
| 分类号 |
C12N15/09;C12N15/56;A61K35/12;A61K38/00;A61K38/46;A61K38/47;A61K47/42;A61K48/00;A61P9/00;A61P13/12;A61P35/00;A61P43/00;C07K14/61;C07K19/00;C12N5/10;C12N9/40;C12N15/62;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
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