NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION.

摘要

The present invention relates to a compound represented by the general formula(I): wherein Ra and Rb are each independently hydrogen atom or lower alkyl, or alternatively Ra and Rb are combined together to form -CH2 -; Rc is halogen atom; Rd is halogen atom or methyl substituted with one to three halogen atoms; X is CH,N, etc. ; and W is selected from: wherein W1 is hydrogen atom, halogen atom, etc., or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition or antitumor agent containing the same; and combinations of the antitumor agent with other antitumor agent(s).