发明名称 Compounds and their use as positive AMPA receptor modulators
摘要 The invention provides novel compounds represented by the general formula compound represented by the formula: wherein the bond represented by the broken line may be a single, a double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R<SUP>2</SUP>; X represents SO<SUB>2 </SUB>or C-O or CH<SUB>2</SUB>; Y represents -CH(R<SUP>4</SUP>)-, -N(R<SUP>4</SUP>)- or -N(R<SUP>4</SUP>)-CH<SUB>2</SUB>-, O; and the meaning of R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, and R<SUP>8 </SUP>are as defined in the application The compounds are useful as positive modulators of the AMPA-receptor.
申请公布号 US7235548(B2) 申请公布日期 2007.06.26
申请号 US20030642224 申请日期 2003.08.18
申请人 NEUROSEARCH A/S 发明人 GOULIAEV ALEX HAAHT;LARSEN MOGENS;VARMING THOMAS;MATHIESEN CLAUS;JOHANSEN TINA HOLM;SCHEEL-KRUGER JORGEN;OLSEN GUNNAR M.;NIELSEN ELSESBET OSTERGAARD
分类号 C07D285/26;A61K31/5415;C07D239/90;C07D285/24;C07D285/28;C07D417/04;C07D417/12;C07D513/04 主分类号 C07D285/26
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