| 发明名称 |
COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS. |
| 摘要 |
<p>One aspect of the present invention relates to isoxazoline derivatives that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising an isoxazoline derivative of the invention. The present invention provides methods for treating and modulating disorders associated with hyper proliferation, such as cancer.</p> |
| 申请公布号 |
MXPA06014754(A) |
申请公布日期 |
2007.06.22 |
| 申请号 |
MX2006PA14754 |
申请日期 |
2005.06.17 |
| 申请人 |
INFINITY PHARMACEUTICALS, INC. |
发明人 |
ALFREDO C. CASTRO;WEI DENG;KRISTOPHER M. DEPEW;MICHAEL A. FOLEY;CHRISTIAN C. FRITZ;ASIMINA T. GEORGES EVANGELINOS;MICHAEL J. GROGAN;NAFEEZA HAFEEZ;EDWARD B. HOLSON;BRIAN T. HOPKINS;NII O. KONEY;TAO LIU;DAVID A. MANN;LISA A. MARCAURELLE;DANIEL A. SNYDER;DENNIS J. UNDERWOOD;ANDREW A. WYLIE;LIN-CHEN YU;LINPING ZHANG |
| 分类号 |
C07D261/02 |
主分类号 |
C07D261/02 |
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