INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-A MODULATORS; SYNTHESES OF SUCH MODULATORS AND METHODS OF USING SUCH MODULATORS
摘要
Compounds are disclosed that have the chemical structure of Formula (II), (IIA) and (IIB) and their prodrug esters and acid-addition salts, and that are useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of various diseases, wherein the R groups are defined in the claims.
申请公布号
WO2007015757(A3)
申请公布日期
2007.06.21
申请号
WO2006US27385
申请日期
2006.07.14
申请人
NEREUS PHARMACEUTICALS, INC.;PALLADINO, MICHAEL A.;THEODORAKIS, EMMANUEL A.;MACHERLA, VENKAT RAMI REDDY;CHAO, TA-HSIANG;SUH, YOUNG GER
发明人
PALLADINO, MICHAEL A.;THEODORAKIS, EMMANUEL A.;MACHERLA, VENKAT RAMI REDDY;CHAO, TA-HSIANG;SUH, YOUNG GER