COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLTL ANTAGONIST FOR TREATING CANCER
摘要
The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists.
申请公布号
WO2007068895(A1)
申请公布日期
2007.06.21
申请号
WO2006GB04611
申请日期
2006.12.12
申请人
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BROWN, JEFFREY, LESTER;EMERY, STEPHEN, CHARLES;BLAKEY, DAVID, CHARLES
发明人
BROWN, JEFFREY, LESTER;EMERY, STEPHEN, CHARLES;BLAKEY, DAVID, CHARLES