发明名称 CATHEPSIN CYSTEINE PROTEASE INHIBITORS
摘要 This invention relates to a novel class of compounds, diagrammed below, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, D and n are defined therein, which are cysteine protein inhibitors, including, but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone reportion is indicated, such as osteoporosis.
申请公布号 WO2006056047(A9) 申请公布日期 2007.06.21
申请号 WO2005CA01764 申请日期 2005.11.18
申请人 MERCK FROSST CANADA LTD.;GAUTHIER, JACQUES, YVES;LI, CHUN, SING;MELLON, CHRISTOPHE 发明人 GAUTHIER, JACQUES, YVES;LI, CHUN, SING;MELLON, CHRISTOPHE
分类号 C07C255/46;A61K31/275 主分类号 C07C255/46
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