摘要 |
This invention relates to a novel class of compounds, diagrammed below, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, D and n are defined therein, which are cysteine protein inhibitors, including, but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone reportion is indicated, such as osteoporosis.
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申请人 |
MERCK FROSST CANADA LTD.;GAUTHIER, JACQUES, YVES;LI, CHUN, SING;MELLON, CHRISTOPHE |
发明人 |
GAUTHIER, JACQUES, YVES;LI, CHUN, SING;MELLON, CHRISTOPHE |