NOVEL COMPOSITION AND METHOD FOR PRODUCTION THEREOF

摘要

Disclosed are: a hyaluronic acid composition which is purified by, in a purification process, subjecting a biological tissue to a treatment with a protease and a molecular weight fractionation and concentrating or lyophilizing the resulting product without performing a treatment with a quaternary ammonium salt or an organic solvent (e.g., an alcohol); a hyaluronic acid composition having a resistance against the activity of a mammalian hyaluronidase; an inhibitor of the decomposition of a glucosaminoglycan comprising the composition as an active ingredient; and a pharmaceutical, food or cosmetic comprising the composition as an active ingredient.