| 发明名称 |
SPLICING-MEDIATED REGULATION OF GENE EXPRESSION |
| 摘要 |
The present invention relates to methods and compositions for controlling the expression of a target gene, whereby an intron cassette such as INT9, an intronic mec-2-derived element, is incorporated into the target gene and expression of the product of the target gene is conditional upon functional expression of the RNA processing protein, mec-8.
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| 申请公布号 |
WO2006119356(A3) |
申请公布日期 |
2007.06.21 |
| 申请号 |
WO2006US16968 |
申请日期 |
2006.05.02 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;CALIXTO, ANDREA;MA, CHARLES;CHALFIE, MARTIN |
发明人 |
CALIXTO, ANDREA;MA, CHARLES;CHALFIE, MARTIN |
| 分类号 |
C12Q1/68;A61K38/00;C07H21/02;C07H21/04;C07K1/00;C12N15/11;C12N15/63;C12P19/34 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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