| 发明名称 |
Combination of an H3 antagonist/inverse agonist and an appetite suppressant |
| 摘要 |
The present invention relates to pharmaceutical compositions comprising therapeutic combinations comprising: one or more H<SUB>3 </SUB>antagonists/inverse agonists; one or more appetite suppressants selected from the group consisting of CB<SUB>1 </SUB>antagonists/inverse agonists, sibutramine, phentermine and topiramate; and optionally one or more HMG-CoA reductase inhibitors. The invention also relates to medicaments and kits comprising the pharmaceutical compositions of the present invention, and methods of treating obesity, obesity related disorders and diabetes using the pharmaceutical compositions of the present invention.
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| 申请公布号 |
US2007142369(A1) |
申请公布日期 |
2007.06.21 |
| 申请号 |
US20060640729 |
申请日期 |
2006.12.18 |
| 申请人 |
VAN HEEK MARGARET;HWA JOYCE J;GRAZIANO MICHAEL P;LACHOWICZ JEAN E;KOWALSKI TIMOTHY J;VELTRI ENRICO P;MCCORMICK KEVIN D;BERLIN MICHAEL Y;ASLANIAN ROBERT G |
发明人 |
VAN HEEK MARGARET;HWA JOYCE J.;GRAZIANO MICHAEL P.;LACHOWICZ JEAN E.;KOWALSKI TIMOTHY J.;VELTRI ENRICO P.;MCCORMICK KEVIN D.;BERLIN MICHAEL Y.;ASLANIAN ROBERT G. |
| 分类号 |
A61K31/541;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/423;A61K31/428;A61K31/4745;A61K31/496;A61K31/517;A61K31/5377 |
主分类号 |
A61K31/541 |
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