发明名称 |
(1-AZA-BICYCLO[3.3.1] N0N-4-YL)-[5-(IH-INDOL-5-YL)-HETEROARYL]-AMINES AS CHOLINERGIC LIGANDS OF THE N-ACHR FOR THE TREATMENT OF PSYCHOTIC AND NEURODEGENERATIVE DISORDERS |
摘要 |
<p>The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders.</p> |
申请公布号 |
WO2007068475(A1) |
申请公布日期 |
2007.06.21 |
申请号 |
WO2006EP12022 |
申请日期 |
2006.12.14 |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;FREDERIKSEN, MATHIAS;FEUERBACH, DOMINIK;HURTH, KONSTANZE;KOLLER, MANUEL;ROY, BERNARD, LUCIEN |
发明人 |
FREDERIKSEN, MATHIAS;FEUERBACH, DOMINIK;HURTH, KONSTANZE;KOLLER, MANUEL;ROY, BERNARD, LUCIEN |
分类号 |
C07D471/08;A61K31/439;A61P25/00 |
主分类号 |
C07D471/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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