发明名称 |
COMPOUND FOR TREATMENT OF NEURODEGENERATIVE DISEASE |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a polypeptide, etc., for the treatment of conformational disease. <P>SOLUTION: A polypeptide contains a specific amino acid sequence and bonding to a causal protein of conformational disease to inactivate the pathogenic action of the protein; a nucleic acid encoding the polypeptide; and a recombinant expression vector or a recombinant virus containing the nucleic acid in an expressible state. The abnormality in a cell can be recovered by using a molecular mechanism of ALS onset caused by a variant SOD1 protein. <P>COPYRIGHT: (C)2007,JPO&INPIT |
申请公布号 |
JP2007151478(A) |
申请公布日期 |
2007.06.21 |
申请号 |
JP20050352454 |
申请日期 |
2005.12.06 |
申请人 |
UNIV OF TOKYO;TOKYO MEDICAL & DENTAL UNIV |
发明人 |
ICHIJO HIDENORI;SAITO HIDEKI |
分类号 |
C12N15/09;A61K35/12;A61K35/76;A61K38/00;A61K48/00;A61P21/04;A61P25/16;A61P25/28;A61P43/00;C07K7/08;C07K14/47;C12N7/00;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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